DR. S. M. ABDUR RAHMAN
Professor
Professional Experiences:
1. Technical Services Officer, Quality Control Officer and Method development in-Charge: Beximco Pharmaceuticals Ltd., (1.10.1995 to 31.12.1996).
2. Lecturer: Department of Pharmacy, Faculty of Pharmacy, University of Dhaka, Bangladesh (1.1.1997 to 15.2.2002)
3. Assistant Professor, Faculty of Pharmacy, University of Dhaka, (16.2.2002 to 24.4.2008)
4. Japan Science and Technology (JST) post-doctoral research fellow: Osaka University (1.4.2002 to 30.9.2004).
5. Japan Society of Promotion of Science (JSPS) fellow: Graduate School of Pharmaceutical Sciences, Osaka University (1.10.2004 to 30.9.2006).
6. Assistant Professor: Graduate School of Pharmaceutical Sciences, Osaka University (1.10.2006 to 29.2.2008)
7. Associate Professor: Department of Clinical Pharmacy and Pharmacology, University of Dhaka (25.4.2008 to 29.4.2012)
8. Professor: Department of Clinical Pharmacy and Pharmacology, University of Dhaka, (30.4.2012 to date)
9. Dean: Faculty of Pharmacy, University of Dhaka (19.1.2017 to date; being elected twice in the Faculty of Pharmacy)
10. Chairman, Department of Clinical Pharmacy and Pharmacology, University of Dhaka (30.5.2020 to 29.5.2023)
11. Visiting Professorship Under the JSPS Bridge fellowship program in Osaka University Japan (Sep 16, 2022 to Oct, 15 2023)
12. Chairman, Department of Pharmacy, University of Dhaka (February 2024 to September 2024)
13. Director, Biomedical Research Center, University of Dhaka. (18.5.2023 to date)
Others leading adminstrative/professional role:
1. House Tutor, Sahidullah Hall, Dhaka University (3rd July 2001 to 1st April 2002)
2. Convenor, Osakabashi (Bangladeshi organization in Osaka, Japan) (2005-2007)
3. Student Advisor, Faculty of Pharmacy (Jan 2010 to Dec 2016)
4. Assistant Proctor, University f Dhaka, (7.12.11 to February 22, 2017)
5. Executive Member, Pharmacy Council of Bangladesh (January 2017 to date)
6. President, Dhaka University Pharmacy Alumni Association (DUPAA) (Janury 2017 to 26.1.2022)
7. Executive Member, Dhaka University Teachers Association (DUTA) (Jan 2017 to Dec 2017)
8. Senate Member, University of Dhaka (April 2017 to April 2020 and May 2022 to date)
Research Work
Current Research:
1. Clinical Trails against COVID-19: Recently, we have Completed the First Randomized Doble-blind Placebo Controlled Clinical Trials of Favipiravir on Hospitalized COVID-19 Patients in Bangladesh. The trial was registered in NIH Clincal.Trial.gov (NCT04402203) I was involved in this Trials an advisory investigator The Trials were conducted in four govt. hospitals in Bangladesh and we obtained very interesting results. The results will be published soon in high-impact health journal.
2. Bioactivity Directed Phytochemical Investigations of Indigenous Plants: My group is working on bioactivity directed phytochemical investigation of various plants of Bangladesh. Extensive antidiabetic studies of some medicinal plant were also being accomplished in collaboration with Prof. Begum Rokeya, BIRDEM, Dhaka.
3. Synthesis of Biological Investigations of Benzimidazole and Nitazoxanide derivatives: Extensive biological evaluations of synthesized compounds having benzimidazole structure are conducted to develop new therapeutic candidates.
4. Development of Novel Bridged Nucleic Acids for Gene Therapy and Diagnosis: This is HEQEP project funded by World bank/UGC. Bridged Nucleic Acids (BNA) are potential therapeutic tool for gene therapy. In this project, Novel highly functional BNA has been developed and their utility in gene therapy and diagnosis will be evaluated.
5. Synthesis and Pharmacological evaluation of Sugar and Nucleosides: Several sugar and nucleoside derivatives were synthesized and their pharmacological effects were investigated. Recntly arylamide sugar and sugar-Benzimidazole hybrids were also synthesized and evaluated.
Research grants received:
1) UGC grants 2009 (1,00000 Tk.)
2) UGC-JSPS (Japan Society of Promotion of Science) bilateral grants 2009-2011 (US$ 75,000)
3) TWAS Research grants from Italy 2009-2010 (US$ 11000)
4) Bangladesh Ministry of Science and Technology 2011-12 (8,00,000.00 Tk.)
5) AIF grant from World Bank for HEQEP project (2012-15): 343,67,000.00 TK
6) Bangladesh Ministry of Science and Technology 2013-14 (4,00,000.00 Tk.)
7) Grants from Ministry of Education 2013-14 (1,300,000.00 TK)
8) AIF grant from HEQEP, UGC (2017-2018) (5,000,000.00 TK)
Award received:
1) Dean’s Award” from the Faculty of Biological Science, DU for outstanding academic performances and regularity.
2) Awarded “Books prize” from Dhaka University for outstanding results in B. Pharm. And M. Pharm. Exams.
3) Awarded “Monbusho Scholarship” by Ministry of Science Education and Culture of Japan
4) Japan Science and Technology Corporation (JST) Post-doctoral fellowship award
5) Japan Society of Promotion of Science (JSPS) Post-doctoral Fellowship award.
6) UGC-JSPS joint projects award from JSPS and UGC.
7) TWAS Young Scientists award in Biological Science 2010.
8) Invitation and awards from Frater Raze Pharmaceuticals, Algeria 2015
9) Gold Medal Award (Dr M Innas Ali Memorial) in Biological Science 2019, Bangladesh Academy of Science
10) Best researcher Award, International Infectious disease, Pencis.
Research interests:
1. Target oriented organic synthesis for developing novel therapeutic agent or improving the existing synthetic pathway.
2. Drug synthesis, structural modifications, SAR analysis
3. Nucleosides, Nucleotides and Nucleic acid chemistry and related biology.
4. Bioorganic and Medicinal Chemistry related topics: synthesis of target molecules and their application to biological process.
5. Transition metal catalyzed reactions (cyclization or various cross-coupling reactions) and their possible applications to develop various structures to be useful for biological and non-biological processes.
6. Clinical Trails and Clinical research.
Research Results in an Important Book in USA:
Scopadulin: in: Dead Ends and Detours: Direct Ways to Successful Total Synthesis. by Sierra, M. A., de la Torre, Fwd. By Nicolau, K. C. Willey and Sons, (2005) NY, USA, pp 31-40.
1) Anjum, J.; Spriha, SE.; Hossain, MS.; Rahman, S. M. A. Computational assessment of Cleradane type furano diterpenoid from Tinospora Crispa: A potential source of anticancer lead compounds. J. Molecular Graphics and Modelling 2026, 109312.
2) Khatun, MCS.; Muhit, MA.; Maruf, MMH.; Iqbal, MA,; Rahman, SMA. Pharmacological evaluation of mangrove plant Rhizophora mucronate (Lam.) grown in the coastal area of Sundarbans. PlosOne 2026, https://doi.org/10.1371/journal.pone.0340646 (IF= 2.6)
3) Khanum, S.; Hossain, H.; Sohrab, M. H.; Rahman, S.M.A Anti-nociceptive and Anti-Inflammatory Potential of Stem Bark Fractions of Dalbergia candenatensis (Dennst.) Prain: Insights from Experimental Models into Underlying Mechanisms. Pharmacology & Pharmacy 2025, 16(9), 323-339.
4) Podder, SK; Saha, P.; Spriha, SE.; Rahman, SMA. Synthesis, In vivo and In silico Evaluation of Analgesic, Antiinflammatory and AntiDiarrheal activities of Benzimidazole Derivatives. ChemistrSelect 2025, 10 (9), e202401267. (IF = 2.0;)
5) Ananta, MF; Saha, P.; Spriha, SE.; Rahman, SMA.; Chowdhury, AKA. Synthesis, Analgesic, Antiinflammatory and Antidiarrheal properties of synthesized Benzimidazole Derivatives via In vivo and In silico methods. Dhaka Univ. J. Pharm. Sc. 2024, 23 (2), 157-169.
6) Tabassum, N.; Spriha, SE.; Saha, P.; Rahman, FI.; Hossain ASMMA, Rahman, SMA. Synthesis and pharmacological evaluation of Heteroarylamide derivatives as potential analgesic, anti-inflammatory, antidiarrheal and Cytotoxic agents. Heliyon 2024, 10 (23), e40630. (IF = 3.6)
7) Tasneem, F., Saha, P., Spriha, S. E., Rahman, F. I., Sharmin, N., Rahman, S. M. A. Isolation, Chemical Modification and In Vivo Pharmacological Screening of Piperine and Its derivative. Dhaka Univ. J. Pharm. Sci. 2024, 23(1), 13-22.
8) Ananta MF; Saha P; Rahman, FI; Spriha, SE.; Chowdhury, AKA.; Rahman, SMA. Design, Synthesis and computational study of benzimidazole derivatives as potential anti-SARS-CoV-2 agents. Journal of Molecular Structure 2024, 1306, 137940. (JIF = 4.73).
9) Rahman, S. M. A., Ahmed, T., Asaduzzaman, M, Rahman, F. I., Chowdhury, A. K. A. Broad-spectrum antimicrobial, anti-inflammatory and pheripheral analgesic activities of heteroaryl nitazoxanide analogs. Egypt. Pharm. J. 2024, 23, 348-358. (JIF = 0.7).
10) Halder, S., Afrose, S.; Shill, M. C., Sharmin, N., Mollick, P. P., Shuma, M. L., Muhit, M. A., Rahman, S. M. A. Self-micellizing solid dispersion of thymoquinone with enhanced biopharmaceutical and nephroprotective effects. Drug Delivery 2024, 31(1), 2337423. (JIF = 8.1). 6
11) Hossain, M. J., Jabin, N., Ahmed, F., Sultana, A. Rahman, S. M. A., Islam, M. R. Irrational use of antibiotics and factors associated with antibiotic resistance: Findings from a cross-sectional study in Bangladesh. Health Science Reports 2023, 8(6), e1465. (JIF = 2.1)
12) Akter, M., Mahmud, Z. A., Uddin, M. M. N., Das, R., Rahman, S. M. A. Synthesis of Naproxen esters and Evaluation of their in vivo and in silico analgesic and anti-inflammatory activities. Dhaka Univ. J. Pharm. Sci. 2023, 22(1), 105-114.
13) Sanam, S., Halder, S., Rahman, S. M. A. Simultaneous Pharmacokinetic Evaluation of pantoprazole and Vitamin B Complex for assessing Drug-Drug Interactions in Healthy Bangladeshi Adults by a Newly Developed and Validated HPLC Method. Separations 2023, 10 (3), 170. (JIF = 2.7).
14) Paul, S. R., Saha, P., Rahman, F. I., Dhar, S., & Rahman, S. M. A. Preferential Synthesis and Pharmacological Evaluation of Mono‐and Di‐substituted Benzimidazole Derivatives. ChemistrySelect, 2022, 7(37), e202201710. (JIF = 2.0)
15) Sultana A, Spriha SE, Rahman SMA, Antioxidant, Analgesic, Antimicrobial and Molecular Docking Studies of the Leaves of Oroxylum Indicum. Dhaka Univ. J. Pharm. Sci. 2022, 21(1), 85-94.
16) Hossain F, Rahman FI, Saha P, Mikami A, Osawa T, Obika S, Rahman SMA. Synthesis of Sugar and Nucleoside Analogs and Evaluation of their Anticancer and Analgesics Potentials. Molecules 2022, 27(11), 3499. (JIF = 4.6)
17) Rahman SMA, Kabir A, Abdullah ABM, Alam MB, Azad KAK, Miah MT, Mowla SGM, Deb SR, Amin MR, Asaduzzaman M. Safety and Efficacy of Favipiravir for the Management of COVID-19 patients: A preliminary Randomized Control Trial. Clin. Infect. Pract. 2022, 15, 100145. (Published by British Infection Association, a companion Journal of Journal of Infection (JIF = 1.4)
18) Hossain MJ, Ahmed F, Khandokar L, Rahman SMA, Hrdidoy A. Ripa FA, Emran TB, Islam R, Mitra S. Alam, M. Status of Psychological health of students following the extended university clsure in Bangladesh: Result from a web-based cross-sectional study. Plos Global Public Health 2022, 2(3), e0000315. (JIF = 2.5)
19) Saha, P.; Rahman, F.I.; Hossain, F.; Rahman, S. M. A.; Rahman, M. M. Antimicrobial diterpenes: Recent development from natural sources. Frontiers in Pharmacology 2022, 12, art 820312. (JIF = 4.8)
20) Spriha, S. E.; Rahman, S. M. A. In silico Evaluation of Selected Compounds from Bergenia ciliata (Haw.) Sternb against Molecular Targets of Breast Cancer. Ind. J. Pharm. Edu Res. 2022, 58 (1), S105-S114 DOI: 10.5530/ijper.56.1s.49 (JIF = 0.8)
21) Raka, S. C.; Rahman, A.; Hossain, F.; Rahman, S. M. A. Synthesis, Characterization and in-vitro, in vivo, in-silico biological evaluations of substituted benzimidazole derivatives, Saudi J. Biol. Sci, 2022, 29(1), 239-250. https://doi.org/10.1016/j.sjbs.2021.08.082 (JIF = 4.33)
22) Spriha SE, Rahman SMA. A Review on Biological Activities of Sugar and Sugar Derivatives. Dhaka Univ. J. Pharm. Sci. 2021, 20(3), 381-394.
23) Khatun, M.C.S.; Muhit, A.; Hossain, M.J.; Mansur, M. A.; Rahman, S. M. A. Isolation of phytochemical constituents from Stevia rebaudiana (Bert.) and evaluation of their anticancer, antimicrobial and antioxidant properties via in vitro and in silico approaches. Heliyon 2021, https://doi.org/10.1016/j.heliyon.2021.e08475 (JIF = 4.0)
24) Hussain, F Saha, P.; Rahman, F. I.; Hossain, M. S. Rahman, S. M. A. In Vivo and In silico Evaluation of Analgesic and Hypoglycemic activities of Roots of Acacia nilotica, Azadirachta indica and justice adhatoda. Dhaka Univ. J. Pharm. Sci. 2021, 20(2), 185-197.
25) Bristy, S. R.; Hossain, M. J.; Khandokar, M. U.; Faruque, M. R. I.; Osman, H.; Rahman, S. M. A. A comprehensive account on recent progress in Pharmacological activities of Benzimidazole derivatives. Frontiers in Pharmacology 2021, 762807. doi:10.3389/fphar.2021.762807 (JIF = 4.8)
26) Hossain, M. J., Rahman, S. M. A., Emran, T., Mitra, S., Islam, M., Dhama, K. Recommendation and Roadmap of Mass Vaccination against COVID-19 Pandemic in Bangladesh as a Lower-Middle-Income Country (LMIC). Archives of Razi Institute 2021; 76(6): 1823-1830. doi: 10.22092/ari.2021.356357.1824 (JIF = 0.7)
27) Hossain, M. J.; Ahmmad, F.; Kuddis, M. R.; Rahman, S. M. A. Exploring public awareness and spreading pattern analysis of COVID-19 outbreak in Bangladesh. Bangladesh Journal of Medical Science, 2021, 108-117. (JIF = 1.08)
28) Spriha, S. E., Rahman F. I.; Rahman, S. M. A, Synthesis, in vivo and in silico analgesic and anti-inflammatory studies of α-D-ribofuranose derivatives, Saudi Pharmaceutical Journal, 2021, 29 (9), 981-991, https://doi.org/10.1016/j.jsps.2021.07.017. (JIF = 4.1)
29) Hossain, M. J.; Ahmed, F.; Rahman, S. M. A.; Sanam, S.; Emran, T. B.; Mitra, S. Impact on online education on fear of academic delay and Psychological distress among university students following one year of COVID-19 outbreak in Bangladesh. Heliyon 2021, 7 (6), e07388. https://doi.org/10.1016/j.heliyon.2021.e07388. (JIF = 4.0)
30) Saha, P; Brishty, S. R.; Rahman, S. M. A. Pharmacological Screening of Substituted Benzimidazole Derivatives. Dhaka Univ. J. Pharm. Sci. 2021, 20, 95-102.
31) Ahmed T, Rahman SMA, Asaduzzaman M, Islam ABK, Chowdhury AKA. Synthesis, in vitro bioassays, and computational study of heteroaryl nitazoxanide analogs. Pharmacol Res Perspect. 2021, 9, e00800. https://doi.org/10.1002/prp2.800. (JIF = 2.6)
32) Alam, S.; Kamal, T. B.; Sarkar, M. M. R.; Zhou, J-R; Rahman, S. M. A.; Mohamed, I. N. Therapeutic effectiveness and safety of repurposing drugs for the treatment of COVID-19: Positions standing in 2021. Front. Pharm. 2021, 12. 659577. doi: 10.3389/fphar.2021.659577 (JIF = 4.8)
33) Hossain MJ, Hridoy A, Rahman SMA, Ahmmed F. Major Depressive and Generalized Anxiety Disorders Among University Students During the Second Wave of COVID-19 Outbreak in Bangladesh. Asia Pac J Public Health 2021, 33(5), 676-678. doi:10.1177/10105395211014345 (JIF = 0.9)
34) Saqueeb, N, Rahman, MM, Munia AT, Rahman SMA, Muhit MA, Sikdar KMYK. A cross sectional study on prevalence of self-medication practice among the students of University of Dhaka. Int. J. Pharm. Res. 2021, 13(2), 2371-76. (JIF = 0.3)
35) Hossain, M. J.; Rahman, S. M. A. Repurposing therapeutic agents against SARS-CoV-2 infection: most promising and neoteric progress. Expert Rev Antiinfective Therapy. 2021; 19 (8), 1009-1027, Doi:10.1080/14787210.2021.1864327. (JIF = 5.7)
36) Hossain M. J.; Kuddus M. R.; Rahman S. M. A. Knowledge, attitudes, and behavioral responses toward COVID-19 during early phase in Bangladesh: a questionnaire-based study. Asia Pac J Public Health 2021. 33 (1), 141-44. DOI: 10.1177/1010539520977328. (JIF = 0.9)
37) Sultana, C.; Azad, M. A. K.; Rahman, M. M.; Muhit, M. A.; Rahman, S. M. A. Phytochemical and Biological Investigation of Stevia rebaudiana (Bert.) Leaves Grown in Bangladesh. Dhaka Univ, J. Pharm. Sci. 2020, 19, 191-97.
38) Rahman, F. I.; Hossain, F.; Saqeeb, N.; Rahman, S. M. A. Synthesis and evaluation of pharmacological activities of some 3-O-benzyl-4-C-(hydroxymethyl)-1,2-O-isopropylidene-α-D-ribofuranose derivatives as potential anti-inflammatory agents and analgesics. Res. Pharm. Sci. 2020, 15, 209-217. (JIF = 2.1)
39) Brishty, S. R.; Saha, P.; Mahmud, Z. A.; Rahman, S. M. A. Synthesis and Evaluation of Analgesic and antioxidant Activities of substituted Benzimidazole Derivatives. Dhaka Univ, J. Pharm. Sci. 2020, 19, 37-46.
40) Saha, P; Brishty, S. R.; Rahman, S. M. A. Synthesis and Evaluation of Disubstituted Benzimidazole Derivatives as Potential Analgesic and Antidiarrheal Agents. Ind. J. Pharm. Sci. 2020, 82, 222-229. (JIF = 0.5)
41) Fujisaka, A. Hari, Y. Takuma, H. Rahman, S. M. A., Yoshikawa, H. Pang, G.,Imanishi, T. Obika, S. Effective syntheses of 2′,4′-BNANC monomers bearing adenine, guanine, thymine, and 5-methylcytosine, and the properties of oligonucleotides fully modified with 2′,4′-BNANC. Biorg. Med. Chem. (Elsevier Science UK). 2019, 27, 1728 -1741. (JIF = 3.5).
42) Hussain, F., Islam, M. A., Hossain, M. S. Rahman, S. M. A. Investigation of antioxidant potentials of Acacia nilotica, Ocimum sanctum and Alpinia Nigra. J. Biomed. Sci. 2019, 8 (2), 1-5. (JIF = 11.0)
43) Sukul, A. Chowdhury, S.; Podder, S. K.. Saha, S. K., Rahman, S. M. A. A Comprehensive Evaluation of Peripheral Analgesic and Antipyretic Activities of Divalent Metal Complexes of Indomethacin. Daikin University. 2018, 10536/DRO/DU:30166662.
44) Kamal S.; Shaheen S.M.; Rahman M. M.; and Rahman S. M. A. Potential Antimicrobial activity of Achyranthes Bidentata methanol extract against both gram (+)ve and gram (-)ve bacteria. Pharmacology online 2018, 2,223-228.
45) Sanam, S.; Nahar, S.; Saqeeb, N.; Rahman, S. M. A. A Validated RP-HPLC Method and Force Degradation Studies of Fexofenadine Hydrochloride in Pharmaceutical Dosage Form. Dhaka Univ, J. Pharm. Sci. 2018, 17, 43-50.
46) Sukul, A. Chowdhury, S.; Podder, S. K.. Saha, S. K., Rahman, S. M. A. A Comprehensive Evaluation of Peripheral Analgesic and Antipyretic Activities of Divalent Metal Complexes of Indomethacin. Dhaka Univ, J. Pharm. Sci. 2017, 16, 173-178.
47) Bodiuzzaman, B. S., Raka, S. C.; Rahman, A.; Fahim, N. F., Sanam, S. Rahman, S. M. A. Comparative in vitro equivalence evaluation of Fexofenadine hydrochloride 120 mg generic Tablets Marketed in Bangladesh. World J. Pharm. Sci. 2017, 5, 44-50.
48) Sukul, A. Podder, S. K. Haque, S. Saha, S. K.; Das, S. C.; Mahmood, Z. A. Rahman, S. M, A. Synthesis, Characterization and Comparison of Local Analgesic, Anti-Inflammatory, Ulcerogenic Activity of Copper and Zinc Complexes of Indomethacin.. Antiinflamm Antiallergy Agents Med Chem. 2017;15(3):221-233. (JIF = 2.0)
49) Hasan, M. S. Das, N,; Begum, F.; Rahman, S. M. A. Sub-chronic toxicological studies of transition metal complexes of naproxen on sprague-dawley rats. Alexandria, Journal of. Medicine 2017, 53, 345-50, (JIF = 0.9)
50) Hossain, M. A.; Ganguly, A.; Rahman, S. M. A.; Hossain, A.; Hassan, M.; Rahmana, M. S. Amino acid profile of the gelatin extracted from the scales of catla, rohu, grass carp and their mixed type. Bang. J. Zool. 2016, 44, 185-95.
51) Das, N.; Hasan, M. S.; Begum, F.; Saha, S. K.; Rahman, S. M. A. A Detailed Study on Acute Toxicity of Transition Metal Complexes of Naproxen. Toxicology International 2016, 23, 240-45.
52) Hasan, M. S.; Das, N.; Mahmud, Z. A..Rahman, S. M. A. Phar,macological Evaluation of Naproxen Metal Complexes on Antinociceptive, Anxiolytic, CNS Depressant and Hypoglycemic Properties. Adv. Pharmcol. Sci. 2016, Article ID 3040724: http://dx.doi.org/10.1155/2016/3040424. (Hindawi Publisher, USA).
53) Hasan, M. S.; Kayesh, R.; Begum, F.; Rahman, S. M. A. Transition Metal Complexes of Naproxen: Synthesis, Characterization, Forced Degradation studies and Analytical Method Verification. J. Anal. Meth. Chem. 2016, 1-10. (USA). (JIF = 2.6)
54) Podder, S. K.; Saqeeb, N.; Rahman, S. M. A. Synthesis and Biological evaluation of2-Methyl-1H-benzimidazole and 1H-benzimidazole-2yl-Methanol. Dhaka Univ, J. Pharm. Sci. 2016, 15, 83-87
55) Subedi, N. K.; Rahman, S. M. A.; Akbar, M. A. Analgesic and Antipyretic Activities of Methanol extract and its fraction from the root of Schoenoplectus grossus. Evidenced Based Complementary and Alternative Medicine 2016, Article ID 3820704, 8 pages http://dx.doi.org/10.1155/2016/38207043820704. (USA) (JIF = 2.1)
56) Ganguly, A.; Mahmood, Z, A.; Saha, S. K.; Rahman, S. M. A. Anti-nociceptive and anti-diarrheal activities of Manikara zapota leaves in Swiss- albino mice.. Pharmaceutical Biology 2016, 54, 1413-1419. (Taylor and Francois, USA). (JIF = 3.5)
57) Rahman SMA, Kamruzzaman S. Omar D. Antibacterial activity of the crude extract of Piper sar mentosum against psedomonas fuscovaginae Int J. Appl, Biol Pharm. Tech. 2016, 7, 67-72.
58) Hossain, F.; Podder, S. K. Ganguly, A.; Rahman, S. M. A. Investigation of CNS Depressant, Anti-diarrheal and Cytotoxic Activities of Crude Methanolic Extracts of Acacia nilotica and Justicia adhatoda root. Indo Am. J. Pharm. Res. 2016, 6, 3954-3961.
59) Moniruzzaman, M,; Asaduzzaman, M.; Hossain, M. S.; Sarker, J.; Rahman, S. M. A., Rashid, M.; Rahman, M. In-Vitro antioxidant and cholinesterase inhibitory activities of methanol fruit extract of phyllanthus acidus. BMC Complementary and Alternative Medicine 2015, 15,403. (Biomed Central, UK) (JIF = 3.8)
60) Mansura A.; Saha, S. K.; Rahman, S. M. A. Gastroentro-histopathology Studies of Synthesized Naproxen esters in Young Healthy Sprague-Dawly rat Model. Dhaka Univ, J. Pharm. Sci. 2015, 14, 49-53.
61) Mantaj, J; Rahman S. M. A.; Bokshi, B.; Hasan, C. M.; Jackson, P. J. M.; Parsons, R. B.; Rahman, K. M. Crispane E, a cis—cleredon diterpene inhibits STAT3 dimerization in breast cancer cells. Org. Biomol. Chem. 2015, 13, 3882-85. (Royal Society of Chemistry, UK) (Impact factor: 3.2)
62) Ganguly, A.; Rahman, S. M. A. Evaluation of the Cytotoxic, Antimicrobial, Antioxidant, Anthelmintic and CNS Depressant Activities of Manilkara zapota Leaf (Sapotaceae). World Journal of Pharmaceutical Research 2015, 4, 272-283.
63) Sukul, A.; Das S. C.; Saha, S. K.; Rahman, S. M. A. screening of analgesic, antimicrobial, cytotoxic and antioxidant activities of metal complexes of indomethacine. Dhaka Univ. J. Pharm. Sci. 2014, 13, 175-180.
64) Hussain F, Ganguly, A., Hossain, M. S., Rahman, S M A. analgesic and antidiarrheal activities of Lagestroemia speciosa roots in experimental animal model Dhaka Univ. J. Pharm. Sci. 2014, 13, 57-62.
65) Mohanta, M. C.; Ganguly, A.; Begum, F.; Rahman, S. M. A. Evaluation of Antinociceptive properties of drynaria quercifolia rhizome in Swiss albino mice. J. Pharm. Res. 2014, 8, 41-44.
66) Hamiduzzaman, M., Mannan, S. J., Dey, A., Rahman, S. M. A. Evaluation of analgesic, antipyretic, hypoglycemic and CNS depressant activity of 2-bromopropylamine hydrobromide, 3-bromopropyl ammonium bromide, ortho amino aniline and benzimidazole-2-thiol. Der Pharmacia Lett. 2014, 6 (1), 47-53.
67) Mohanta, M. C; Ganguly, A.; Begum F.; Rahman, S. M. A. Evaluation of anti-nociceptive properties of Drynaria quercifolia rhizome in Swiss-albino mice. J. Pharm. Res. 2014, 8(1), 41-44. Available from: http://jpronline.info/ (Impact factor: 4.2)
68) Hossain M. M.; Even A. S. M.I. H.; Akbar M. A.; Ganguly, A.; Rahman, S. M. A. Evaluation of analgesic activity of Sterculia villosa Roxb. bark in Swiss-Albino mice. Dhaka Univ. J. Pharm. Sci. 2013, 12(2), 125-129. Available from: http://www.banglajol.info/index.php/JPharma
69) Ganguly, A.; Mahmood, Z, A.; Uddin, M. N.; Rahman, S. M. A. In-Vivo anti-inflammatory and antipyretic activities of Manikara zapota leaves in albino Wister rats. Asian Pac. J. Trop. Dis. 2013, 3, 301-307. (JIF = 3.5)
70) Islam, M. A., Mahmud, Z. A., Rahman, S. M. A. Moniruzzaman, M. D., Saha, S. K. Evaluation of thrombolytic activity and brine shrimp lethality bioassay of methanol extracts of Tinospora crispa. Int. J. Pharm. Sci. Res. 2013, 4, 1148
71) Noor, S., Rahman, S. M. A., Ahmed Z., Das, A., Hossain, M. M. Evaluation of anti-inflammatory and antidiabetic activity of ethanolic extracts of Desmodium pulchellum Benth. (fabaceae) barks on albino wister rats. J. App. Pharm. Sci. 2013, 3 (7), 125-129. (JIF =1.3).
72) Bokshi, B.; Rahman, S. M. A.; Sadhu, S. K.; Muhammad, A.; Islam, M. A. Assessment of Analgesic and Antidiarrhoeal Activities of Different Fractions of Crude Extract of Stephania Japonica Stem. Int. J. Pharm. Sci. Res. 2013, 4, 1233-1238.
73) Bokshi, B.; Rahman, S. M. A.; Sadhu, S. K.; Muhammad, A,; Assesment of antioxidant,cytotoxic and antibacterial activities of different fractions of crude extract of Stephania japonica stem: ; .Int. J. Pharm. Sci. Res. 2013, 4, 1378-1383.
74) Rahman, S. M. A.; Baba, T.; Kodama, T.; Islam, M. A.; Obika, S. Hybridizing ability and Nuclease rseistance Profiles of Backbone modified Cationic Phosphorothioate Oligonucleotides. Biorg. Med. Chem. (Elscevier Science UK). 2012, 20, 4098. (JIF = 3.5)
75) Dey, A.; Rahman. S. M.A.; Ahsanul Akbor, M.; Hamiduzzaman, M.; Monir Hossain, M. Evaluation of Analgesic and antidiarrhoeal Activity of Whole Plant Boerhavia Repens. Int. Res. J. Pharm. 2012, 3, 102.
76) Dey, A., Shaker, A. A. M., Rahman, S. M. A., Hamiduzzaman, M., Amin, T. evaluation of the Anti-inflammatory and antipyretic activities of the plant Boreroia repens (Family Nyctaginaceae) J. Nat. Prod. Plant. Resour, 2012, 2, 4), 471-474. (JIF = 0.60)
77) Khan, A. R.; Hasan, M.; Rahman, S. M. A. Invitro Antimicrobial and Cytotoxic Activities of Tamarindus Indica Seeds. Int. J. Sust. Agril. Tech. 2011, 7, 13.
78) Torigoe, H.; Rahman, S. M. A.; Takuma, H.; Sato, N.; Imanishi, T. Obika, S. 2’-O, 4-C, -Amino Methylene bridged nucleic acids modification with enhancement of nuclease resistance promotes pyrimidine motif triplex nucleic acid formation at physiological pH: Chem. Eur. J. (Willy-VCH, Germany) 2011, 17,2742. (JIF = 3.7)
79) Torigoe, H.; Rahman, S. M. A.; Takuma, H.; Sato, N.; Imanishi, T. Obika, S. Interrupted 2'- O ,4'- C -Aminomethylene Bridged Nucleic Acid Modification Enhances Pyrimidine Motif Triplex-Forming Ability and Nuclease Resistance Under Physiological Condition
Nucleosides, Nucleotides and Nucleic Acids (Taylor and Francois, USA) 2011, 30, 63-81. (JIF = 1.3)
80) Sultana MS, Islam, MS, Rahman, SMA Mansur MA. Study of surface water and soil quality affected by heavy metals of pbana Sadar. Bang. Sci. Ind Res. 2011, 46, 133-140.
81) Obika, S., Rahman, S. M. A., Fujisaka, A., Kawada, Y., Baba, T., Imanishi, T. Bridged Nucleic Acids: Development, Synthesis, and Properties (Invited Review): Heterocycles (Japan). 2010, 81, 1347-1393 (46 pages). (JIF = 0.6)
82) Rahman, S. M. A., Haitani, S., Imanishi, T. Obika, S. RNA interference with Bridged Nucleic Acids: Biorg. Med. Chem. (Elscevier Science UK). 2010, 18, 3474. (JIF = 3.6)
83) Umeda, R.; Miki, Y. Rahman, S. M. A.; Sonoda, M.; Tobe, Y. Formation of naphthodithiophene isomers by flash vacuum pyrolysis of 1,6-di(2-thienyl)-1,6 di-(3-thienyl)-1,5-hexadien-3-ynes. Comptes Rendus Chimie (Elsevier, France) 2009, 12, 378. (JIF = 1.6)
84) Sasaki, K.; Rahman. S. M. A.; Satoh, N.; Obika, S.; Imanishi, T.; Torigoe, H. Promotion of triplex formation by 3’-amino, 2’-O, 4-C, -Methylene bridged nucleic acid modification. Nucleic Acids Symp. Ser. 2009, 53, 159-160.
85) Rahman, S. M. A., Imanishi, T. Obika, Synthesis of Several Types of Bridged Nucleic Acids: Chem. Lett .(Japan Chemical Society) 2009, 38, 513. (JIF = 1.6)
86) Sasaki, K.; Rahman. S. M. A.; Obika, S.; Imanishi, T.; Torigoe, H. Promotion of triplex formation by 2’-O, 4-C, -Amino Methylene bridged nucleic acids. Nucleic Acids Symp. Ser. (Oxford, UK), 2008, 52, 419-20.
87) Rahman SMA, Solaiman ARM. Assessment of Microbila biomass carbon and Nitrogen in soma tea soils of Bangladesh. Bang. J. Microbiol. 2008, 25, 21-25.
88) Obika, S., Rahman, S. M. A., et al. Synthesis and Properties of 3’-amino-2’,4’-BNA: A Bridged Nucleic Acid with N3, P5 phosphoramidate Biorg. Med. Chem. (Elsevier Science, UK) 2008, 16, 9230. (JIF = 3.5)
89) Rahman, S. M. A., Seki, S. Obika, S., Yoshikawa, H., Miyashita, K. Imanishi, T. Design, Synthesis and Properties of 2’,4’-BNANC: A Bridged Nucleic Acid Analogue; J. Am. Chem. Soc. (American Chemical Society) 2008, 130, 4886. (JIF = 15.0)
90) Miyashita, K., Rahman, S. M. A., Seki, S., Obika, S., Imanishi, T. N-methyl substituted 2’,4’-BNANC: A highly nuclease resistant Nucleic acid analogue with high-affinity RNA selective hybridization; Chem Commun. (Royal Society of Chemistry, UK), 2007, 3765. (JIF = 4.2)
91) Rahman, S. M. A., Seki, S., Obika, S. Haitani, S., Miyashita, K.. Imanishi, T. Highly Stable Pyrimidine Motif Triplex Formation by 2’,4’-BNANC : A Novel Bridged Nucleic Acid Analogue; Angew. Chem. Int. Ed. (Willy-VCH, Germany), 2007, 46, 4306. (JIF = 16.9)
92) Rahman, S. M. A.; Seki, S.; Utski, K.; Obika, S.; Miyashita, K.; Imanishi, T. of 2',4'-BNANC: A novel Bridged Nucleic Acid Analogue with Excellent Hybridizing and Nuclease Resistance Profiles: Nucleosides, Nucleotides and Nucleic Acids (Taylor and Francois, USA) 2007, 26, 1625. (JIF = 1.3)
93) Rahman, S. M. A.; Seki, S.; Utski, K.; Obika, S.; Miyashita, K.; Imanishi, T. High-affinity RNA Mimicking Binding of 2',4'-BNANC with complementary strands: A comparative study with 2’,4’-BNA/LNA: Nucleic Acids Symp. Ser.(Oxford University Press, UK), 2006, 50, 195-196.
94) Rahman, S. M. A.; Sonoda, M.; Ono, M.; Miki, K.; Tobe, Y. Novel Synthesis of Bridged Phenylthienylethenes and Dithienylethenes via Double Cyclization of Diaryldienynes. Org. Lett. (American Chemical Society, USA), 2006, 8, 1197. (JIF = 5.0)
95) Rahman, S. M. A.; Seki, S.; Utski, K.; Obika, S.; Miyashita, K.; Imanishi, T. Synthesis and Properties of 2',4'-BNANC, a Second Generation BNA: Nucleic Acids Symp. Ser. (Oxford University Press, UK ) 2005, 49, 5-6.
96) Hayashi, K.; Rahman, S. M. A.; Ohno, H.; Tanaka, T.; Toyoka, N.; Hemoto, H.; Hayashi, T. et al. Evaluation of Scopadulciol-Related Molecules for Their Stimulatory Effect on the Cytotoxicity of Acyclovir and Ganciclovir Againnst Herpes Simplex Virus Type I Thymidine Kinase Gene-transfected Hela-Cells: Chem. Pharm. Bull (Pharmaceutical Society of Japan) 2004, 52, 1015-1017. (JIF = 1.7)
97) Rahman, S. M. A.; Sonoda, M.; Itahashi, K.; Tobe. Y. Efficient Synthesis of Biindenylidene Derivatives via a Domino-Heck Type Double Cyclization of Diaryldienynes: Org. Lett. (American Chemical Society, USA) 2003, 5, 3411. (JIF = 5.0)
98) Tanaka, T.; Murakami, K.; Kanda, A.; Patra, D.; Yamamoto, S.; Satoh, N.; Kim, S-W.; Rahman, S. M. A.; Ohno, H.; Iwata, C. Total Synthesis of Stemodinone via an Efficient Ring Exchange Strategy. Pharm. Bull. Josai Univ. 2003, 4, 1-31.
99) Rahman, S. M. A.; Ohno, H.; Tanaka, T. Improved Method of an Unusual Conversion of Aliphatic Amines into Alcohols: Tetrahedron Lett. (Elsevier Science, UK), 2001, 42, 8007. (JIF = 1.5)
100)Tanaka, T.; Murakami, K.; Kanda, A.; Patra, D.; Yamamoto, S.; Satoh, N.; Kim, S-W.; Rahman, S. M. A.; Ohno, H.; Iwata, C. Total Synthesis of Stemodinone via an Efficient Ring Exchange Strategy. J. Org. Chem. (American Chemical Society, USA), 2001, 66, 7107. (JIF = 3.6)
101)Rahman, S. M. A.; Ohno, H.; Murata, T.; Yoshino, H.; Satoh, Murakami, K.; Patra, D.; Iwata, C.; Maezaki, N.; Tanaka, T. Scopadulin no jen gosei: Tennen Yuki Torenkai. 2001, 605-610.
102)Rahman, S. M. A.; Ohno, H.; Murata, T.; Yoshino, H.; Satoh, Murakami, K.; Patra, D.; Iwata, C.; Maezaki, N.; Tanaka, T. The First Total Synthesis of (±) Symp. Chem. Nat. Prod. 2001, 605-610.
103)Rahman, S. M. A.; Ohno, H.; Murata, T.; Yoshino, H.; Satoh, Murakami, K.; Patra, D.; Iwata, C.; Maezaki, N.; Tanaka, T. Total Synthesis of Scopadulin: J. Org. Chem. (American Chemical Society, USA), 2001, 66, 4831. (JIF = 3.6)
104)Rahman, S. M. A.; Ohno, H.; Murata, T.; Yoshino, H.; Satoh, N.; Murakami, K.; Patra, D.; Iwata, T.; Maezaki, N.; Tanaka, T. The First Total Synthesis of Scopadulin, an Antiviral Aphidicolane Diterpene: Org. Lett. (American Chemical Society, USA), 2001, 3, 619. (JIF = 5.0)
105)Rahman, S. M. A.; Ohno, H.; Yoshino, H.; Satoh, N.; Tsukaguchi, M.; Murakami, K.; Iwata, C.; Maezaki, N.; Tanaka, T. A Model Study for the Total Synthesis of Scopadulin: Stereoselective Construction of A/B Ring System of Scopadulin: Tetrahedron (Elscevier Science, UK), 2001, 57, 127. (JIF = 2.1)
106)Rahman, S. M. A.; Ohno, H.; Maezaki, N.; Iwata, C.; Tanaka, T. Efficient One-step Conversion of Primary Amines to Alcohols: Application to a Model Study for the Total Synthesis of Scopadulin: Org. Lett. (American Chemical Society, USA), 2000, 2, 2893. (JIF = 5.0)
107)Rahman, S. M. A.; Hossain, C. F.; Chowdhury. A. K. A. Study of the Effect of Picroliv, Picroside III, and Kutkoside from Picrorhiza kurooa on Carbon Tetrachloride Treated Partially Damaged Kidney. Bangladesh J. Physiol. Pharmacol. 1999, 15, 55-57.
Patent:
1. Tobe, Y.; Sonoda, M.; Rahman, S. M. A.. Preparation of Asmmetric 1,1-Biindenylidenes. Jpn. Kokai Tokkyo Koho, 2005, 22 pp. CODEN: JKXXAF JP 2005002003 A2.
2. Rahman, S. M. A., Imanishi, T., Obika, S. PCT/JP98/00945 Pat. Appl. PCT/JP98/00945